| DC Field | Value | Language |
|---|
| dc.contributor.author | Melnyk, Sofiia | |
| dc.contributor.author | Ostash, Bohdan | |
| dc.coverage.temporal | 23–25 November 2018, Lviv | |
| dc.date.accessioned | 2020-06-09T07:07:29Z | - |
| dc.date.available | 2020-06-09T07:07:29Z | - |
| dc.date.created | 2018-11-22 | |
| dc.date.issued | 2018-11-22 | |
| dc.identifier.citation | Melnyk S. The Expression of Pleiotropic and Pathway-Specific Regulators of Secondary Metabolism in Clorobiocin Producer Streptomyces Roseochromogenes NRRL3504 / Sofiia Melnyk, Bohdan Ostash // Litteris et Artibus : proceedings, 23–25 November 2018, Lviv. — Lviv : Lviv Politechnic Publishing House, 2018. — P. 218–219. — (7th International academic conference “Chemistry & chemical technology 2018” (CCT-2018)). | |
| dc.identifier.isbn | 978-966-941-294-2 | |
| dc.identifier.uri | https://ena.lpnu.ua/handle/ntb/51770 | - |
| dc.description.abstract | Clorobiocin is potent aminocoumarin against resistant pathogens. We describe attempts to
improve clorobiocin production via expression of pleiotropic (adpA) and pathway-specific regulatory
(cloG, novG) genes in Streptomyces roseochromogenes NRRL3504. Positive influence of adpA on
clorobiocin production was revealed. The effects of cloG and novG are under investigation. | |
| dc.format.extent | 218-219 | |
| dc.language.iso | en | |
| dc.publisher | Видавництво Львівської політехніки | |
| dc.publisher | Lviv Politechnic Publishing House | |
| dc.relation.ispartof | Litteris et Artibus : proceedings, 2018 | |
| dc.subject | Streptomyces | |
| dc.subject | clorobiocin | |
| dc.subject | AdpA | |
| dc.subject | StrR-like regulators | |
| dc.subject | gyrase inhibitors | |
| dc.title | The Expression of Pleiotropic and Pathway-Specific Regulators of Secondary Metabolism in Clorobiocin Producer Streptomyces Roseochromogenes NRRL3504 | |
| dc.type | Conference Abstract | |
| dc.rights.holder | © Національний університет “Львівська політехніка”, 2018 | |
| dc.contributor.affiliation | Ivan Franko National University of Lviv | |
| dc.format.pages | 2 | |
| dc.identifier.citationen | Melnyk S. The Expression of Pleiotropic and Pathway-Specific Regulators of Secondary Metabolism in Clorobiocin Producer Streptomyces Roseochromogenes NRRL3504 / Sofiia Melnyk, Bohdan Ostash // Litteris et Artibus : proceedings, 23–25 November 2018, Lviv. — Lviv : Lviv Politechnic Publishing House, 2018. — P. 218–219. — (7th International academic conference “Chemistry & chemical technology 2018” (CCT-2018)). | |
| dc.relation.references | [1] S. Alt, L.A. Mitchenall, A. Maxwell and L. Heide. “Inhibition of DNA gyrase and DNA topoisomerase IV of Staphylococcus aureus and Escherichia coli by aminocoumarin antibiotics”. J. Antimicrob. Chemother., vol. 66, pp. 2061-2069, 2011. | |
| dc.relation.references | [2] F. Pojer, S.M. Li, and L. Heide. “Molecular cloning and sequence analysis of the clorobiocin biosynthetic gene cluster: new insights into the biosynthesis of aminocoumarin antibiotics”. Microbiology, vol. 148, no. 12, pp. 3901-3911, 2002. | |
| dc.relation.references | [3] L. Heide. “The aminocoumarins: biosynthesis and biology”. Nat. Prod. Rep., vol. 26, no. 10, pp. 1241-1250, 2009. | |
| dc.relation.references | [4] G. Liu, K.F. Chater, G. Chandra, G. Niu and H. Tan. “Molecular regulation of antibiotic biosynthesis in Streptomyces”. Microbiol. Mol. Biol. Rev., vol. 77, no. 1, pp. 112-143, 2013. | |
| dc.relation.referencesen | [1] S. Alt, L.A. Mitchenall, A. Maxwell and L. Heide. "Inhibition of DNA gyrase and DNA topoisomerase IV of Staphylococcus aureus and Escherichia coli by aminocoumarin antibiotics". J. Antimicrob. Chemother., vol. 66, pp. 2061-2069, 2011. | |
| dc.relation.referencesen | [2] F. Pojer, S.M. Li, and L. Heide. "Molecular cloning and sequence analysis of the clorobiocin biosynthetic gene cluster: new insights into the biosynthesis of aminocoumarin antibiotics". Microbiology, vol. 148, no. 12, pp. 3901-3911, 2002. | |
| dc.relation.referencesen | [3] L. Heide. "The aminocoumarins: biosynthesis and biology". Nat. Prod. Rep., vol. 26, no. 10, pp. 1241-1250, 2009. | |
| dc.relation.referencesen | [4] G. Liu, K.F. Chater, G. Chandra, G. Niu and H. Tan. "Molecular regulation of antibiotic biosynthesis in Streptomyces". Microbiol. Mol. Biol. Rev., vol. 77, no. 1, pp. 112-143, 2013. | |
| dc.citation.conference | 8th International youth science forum «Litteris et Artibus» | |
| dc.citation.journalTitle | Litteris et Artibus : proceedings | |
| dc.citation.spage | 218 | |
| dc.citation.epage | 219 | |
| dc.coverage.placename | Львів | |
| dc.coverage.placename | Lviv | |
| Appears in Collections: | Litteris et Artibus. – 2018 р.
|
