https://oldena.lpnu.ua/handle/ntb/49604
Title: | Mathematical model of electrical activity of the biological network areas |
Other Titles: | Математична модель електричної активності ділянок білогічної нейронної мережі |
Authors: | Горячко, Всеволод Гоголюк, Оксана Рижий, Тарас Рендзіняк, Сергій Horyachko, Vsevolod Hoholyuk, Oksana Ryzyi, Taras Rendzinyak, Serhiy |
Affiliation: | Lviv Polytechnic National University |
Bibliographic description (Ukraine): | Mathematical model of electrical activity of the biological network areas / Vsevolod Horyachko, Oksana Hoholyuk, Taras Ryzyi, Serhiy Rendzinyak // Computational Problems of Electrical Engineering. — Lviv : Lviv Politechnic Publishing House, 2019. — Vol 9. — No 2. — P. 8–12. |
Bibliographic description (International): | Mathematical model of electrical activity of the biological network areas / Vsevolod Horyachko, Oksana Hoholyuk, Taras Ryzyi, Serhiy Rendzinyak // Computational Problems of Electrical Engineering. — Lviv : Lviv Politechnic Publishing House, 2019. — Vol 9. — No 2. — P. 8–12. |
Is part of: | Computational Problems of Electrical Engineering, 2 (9), 2019 |
Issue: | 2 |
Volume: | 9 |
Issue Date: | 20-Mar-2019 |
Publisher: | Lviv Politechnic Publishing House |
Place of the edition/event: | Львів Lviv |
Keywords: | mathematical model neuron axon dendrite synapse neural impulse |
Number of pages: | 5 |
Page range: | 8-12 |
Start page: | 8 |
End page: | 12 |
Abstract: | У статті запропоновано математичну модель генерування потенціалу дії та поширення імпульсу у
відростках нейрона на підставі аналізу параметричних
електричних кіл із розподіленими параметрами та математичну модель синаптичних міжнейронних зв’язків.
Розроблені моделі дозволяють враховувати вплив на
проведення нервового імпульсу таких чинників, як
геометричні, фізичні та хімічні параметри відростків
нейронів та наявність різних медіаторів у хімічних
синапсах. Такі моделі можна надалі використати для
дослідження умов збудження нейрона при просторовому і
часовому інтегруванні вхідних сигналів, а також для
моделювання нервово-м’язових з’єднань. In the paper, the mathematical model describing the generation of action potential and propagation of an impulse in the neuron's filaments on the basis of the analysis of parametric electriс circuits with distributed parameters and the mathematical model of synaptic interneuron connections are proposed. Developed models allow taking into account the influence of such factors as geometric, physical and chemical parameters of the neuron's filaments and the presence of different neurotransmitters in chemical synapses on transmitting a neural impulse. Further, such models can be used for investigating the conditions of neuron firing at spatial and time integration of input signals, as well as for the simulation of neuromuscular junctions. |
URI: | https://ena.lpnu.ua/handle/ntb/49604 |
Copyright owner: | © Національний університет “Львівська політехніка”, 2019 |
References (Ukraine): | 1. A. Hodgkin and A. Huxley “A quantitative description of membrane current and its application to conduction and excitation in nerve”, Journal of Physiology, vol. 117, pp. 500–544, 1952. 2. I. Tasaki, “Physiology and Electrochemistry of Nerve Fibers”, Academic Press, 1982. 3. P. Kostiuk, V. Zyma, V. Mahura et al., Biophysics. Kyiv, Oberegy, 2001. (Ukrainian) 4. V. Horyachko, Kh. Drohomyretska, and M. Kotsyuba, “Mathematical model of action potential propogation in neuron axon”, in Proc. VI International Workshop Computational Problems of Electrical Engineering, Zakopane, Poland, September 1–4, pp. 137–138, 2004. 5. V. Horyachko “Mathematical model of the neural impulse propagation in the neuron”, Teoretychna elektrotechnika, Issue 58, pp. 20–26, Lviv, 2005. (Ukrainian) 6. E. N. Marieb, Essentials of Human Anatomy and Physiology. 10th Edition, Benjamin Cummings, 2012. |
References (International): | 1. A. Hodgkin and A. Huxley "A quantitative description of membrane current and its application to conduction and excitation in nerve", Journal of Physiology, vol. 117, pp. 500–544, 1952. 2. I. Tasaki, "Physiology and Electrochemistry of Nerve Fibers", Academic Press, 1982. 3. P. Kostiuk, V. Zyma, V. Mahura et al., Biophysics. Kyiv, Oberegy, 2001. (Ukrainian) 4. V. Horyachko, Kh. Drohomyretska, and M. Kotsyuba, "Mathematical model of action potential propogation in neuron axon", in Proc. VI International Workshop Computational Problems of Electrical Engineering, Zakopane, Poland, September 1–4, pp. 137–138, 2004. 5. V. Horyachko "Mathematical model of the neural impulse propagation in the neuron", Teoretychna elektrotechnika, Issue 58, pp. 20–26, Lviv, 2005. (Ukrainian) 6. E. N. Marieb, Essentials of Human Anatomy and Physiology. 10th Edition, Benjamin Cummings, 2012. |
Content type: | Article |
Appears in Collections: | Computational Problems Of Electrical Engineering. – 2019 – Vol. 9, No. 2 |
File | Description | Size | Format | |
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2019v9n2_Horyachko_V-Mathematical_model_of_electrical_8-12.pdf | 274.82 kB | Adobe PDF | View/Open | |
2019v9n2_Horyachko_V-Mathematical_model_of_electrical_8-12__COVER.png | 1.35 MB | image/png | View/Open |
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