| DC Field | Value | Language |
|---|
| dc.contributor.author | Майкович, О. В. | |
| dc.contributor.author | Носова, Н. Г. | |
| dc.contributor.author | Борденюк, О. Ю. | |
| dc.contributor.author | Фігурка, Н. В. | |
| dc.contributor.author | Варваренко, С. М. | |
| dc.contributor.author | Maikovych, O. V. | |
| dc.contributor.author | Nosova, N. G. | |
| dc.contributor.author | Bordenyuk, O. Yu. | |
| dc.contributor.author | Fihurka, N. V. | |
| dc.contributor.author | Varvarenko, S. M. | |
| dc.date.accessioned | 2020-03-02T09:14:40Z | - |
| dc.date.available | 2020-03-02T09:14:40Z | - |
| dc.date.created | 2019-02-28 | |
| dc.date.issued | 2019-02-28 | |
| dc.identifier.citation | Investigation of sorption/desorption processes of medical substances by combined hydrogels / O. V. Maikovych, N. G. Nosova, O. Yu. Bordenyuk, N. V. Fihurka, S. M. Varvarenko // Chemistry, Technology and Application of Substances. — Lviv : Lviv Politechnic Publishing House, 2019. — Том 2. — № 2. — С. 154–158. | |
| dc.identifier.uri | https://ena.lpnu.ua/handle/ntb/46401 | - |
| dc.description.abstract | Наведено результати досліджень щодо сорбції та десорбції комбінованими поліакриламід-
желатиновими гідрогелями новокаїну та лідокаїну. Показано, що сорбція/десорбція гідрогелями
проходить з різною швидкістю залежно від будови та наявності функціональних груп у структурі
речовин, що сорбуються. Під час дослідження десорбції лікарських речовин з полімерної матриці
гідрогелю встановлено, що вивільнення новокаїну та лідокаїну відбувається доволі тривалий час, що
може забезпечити їх пролонговану доставку. Розроблені гідрогелеві матеріали можуть бути
використані в косметології і медицині як трансдермальні системи доставки ліків. | |
| dc.description.abstract | The article represents the results of studies of sorption and desorption of novocaine and
lidocaine by combined polyacrylamide gelatinous hydrogels. The rates of sorption by hydrogels are
different, depending on the structure and the presence of functional groups in the structure of
absorbed substances. The study of the desorption of medicinal substances from the polymeric
matrix of hydrogel showed that release of novocaine and lidocaine lasts for a long time, which can
ensure their prolonged delivery. Developed hydrogel materials can be used in cosmetology and
medicine, as transdermal drug delivery systems. | |
| dc.format.extent | 154-158 | |
| dc.language.iso | en | |
| dc.publisher | Lviv Politechnic Publishing House | |
| dc.publisher | Lviv Politechnic Publishing House | |
| dc.relation.ispartof | Chemistry, Technology and Application of Substances, 2 (2), 2019 | |
| dc.subject | гідрогель | |
| dc.subject | колаген | |
| dc.subject | желатин | |
| dc.subject | сорбція | |
| dc.subject | новокаїн | |
| dc.subject | лідокаїн | |
| dc.subject | hydrogel | |
| dc.subject | collagen | |
| dc.subject | gelatin | |
| dc.subject | sorption | |
| dc.subject | novocaine | |
| dc.subject | lidocaine | |
| dc.title | Investigation of sorption/desorption processes of medical substances by combined hydrogels | |
| dc.title.alternative | Дослідження процесів сорбції/десорбції лікарських речовин комбінованими гідрогелями | |
| dc.type | Article | |
| dc.rights.holder | © Національний університет „Львівська політехніка“, 2019 | |
| dc.contributor.affiliation | Національний університет “Львівська політехніка” | |
| dc.contributor.affiliation | Lviv Polytechnic National University | |
| dc.format.pages | 5 | |
| dc.identifier.citationen | Investigation of sorption/desorption processes of medical substances by combined hydrogels / O. V. Maikovych, N. G. Nosova, O. Yu. Bordenyuk, N. V. Fihurka, S. M. Varvarenko // Chemistry, Technology and Application of Substances. — Lviv : Lviv Politechnic Publishing House, 2019. — Vol 2. — No 2. — P. 154–158. | |
| dc.relation.references | 1. Chai, Q., Jiao, Y, Yu, X.. (2017). Hydrogels for biomedical applications: their characteristics and the mechanisms behind them. Gels, 3(6), 1-15. | |
| dc.relation.references | 2. Hennink, W., Van Nostrum, C. (2012). Novel crosslinking methods to design hydrogels. Advanced Drug Delivery Reviews, 64, 223-236. | |
| dc.relation.references | 3. Seliktar, D. (2012). Designing cell-compatible hydrogels for biomedical applications. Science, 336 (6085), 1124–1128. | |
| dc.relation.references | 4. Hamidi, M., Azadi, A., Rafiei, P. (2008). Hydrogel nanoparticles in drug delivery. Advanced Drug Delivery Reviews, 60, 1638-1649. | |
| dc.relation.references | 5. Vasilev, A. E., Krasnyuk, I. I., Ravikumar, S. (2001). Transdermalnyie terapevticheskie sistemyi dostavki lekarstvennyih veschestv. Himikofarmatsevticheskiy zhurnal, 35(11), 29-42. | |
| dc.relation.references | 6. Samchenko, Yu. M., Pasmurtseva, N. A., Ulberg Z. R. (2007). Diffuziya lekarstvennyih preparatov iz gidrogelevyih nanoreaktorov. Dopovidi NAN Ukrayini, 6, 143-148. | |
| dc.relation.references | 7. Sekine, Y.,Moritani, Y., Fukazawa, T. I., Sasaki, Y., Akiyoshi, K. (2012). A hybrid hydrogel biomaterial by nanogel engineering: bottom-up design with nanogel and liposome building blocks to develop a multidrug delivery system. Advanced healthcare materials, 1(6), 722-728. | |
| dc.relation.references | 8. Wen Zhao, Jin Xing, Cong Yang, Liu Yuying, Fu Jun. (2013). Degradable natural polymer hydrogels for articular cartilage tissue engineering. Journal of Chemical Technology & Biotechnology, 88(3), 327-339. | |
| dc.relation.references | 9. Naahidi, S., Jafari, M., Logan, M., Wang, Y., Yuan, Y., Bae, H.,. Dixon, B, Chen, P. (2017). Biocompatibility of hydrogel-based scaffolds for tissue engineering applications. Biotechnology Advаnces, 35(5), 530-544. | |
| dc.relation.references | 10. J. Tavakoli, Y. Tang Honey. (2017). PVA hybrid wound dressings with controlled release of antibiotics: Structural, physico-mechanical and in vitro biomedical studies. Materials Science and Engineering, 77, 318–325. | |
| dc.relation.references | 11. J. Ramshaw, J. Werkmeister, V. Glatteur. (1995). Collagen based biomaterials. Biotechnol. Rev.,13, 336-382. | |
| dc.relation.references | 12. Amir K. Miri, Hossein Goodarzi, Berivan Cecen, Shabir Hassan, Yu Shrike Zhang. (2018). Permeability mapping of gelatin methacryloyl hydrogels. Acta Biomaterialia,77, 38-47. | |
| dc.relation.references | 13. Nosova, N. G., Samarik, V. Yа., Varvarenko, S. M., Ferens, M. V., Voronovska, A. V., Nagornyak, M. І., Homyak, S. V., Nadashkevich, Z. Yа., Voronov, S. A. (2016). Polyacrylamide porous hydrogels – preparation and properties Voprosyi himii i himicheskoy tehnologiі, 5-6, 78-86. | |
| dc.relation.references | 14. Lavrova, I.S. (1983). Praktikum po kolloidnoy himii. Moscow., Vyisshaya shkola. | |
| dc.relation.references | 15. Samchenko, Yu. M., Pasmurtseva, N. A., Ulberg, Z. R. (2010). Primenenie uf-spektroskopii dlya izucheniya diffuzii lekarstvennyih soedineniy iz gidrogeley meditsinskogo. Jurnal hromatografіchnogo tovaristva,10(1), 4-24. | |
| dc.relation.referencesen | 1. Chai, Q., Jiao, Y, Yu, X.. (2017). Hydrogels for biomedical applications: their characteristics and the mechanisms behind them. Gels, 3(6), 1-15. | |
| dc.relation.referencesen | 2. Hennink, W., Van Nostrum, C. (2012). Novel crosslinking methods to design hydrogels. Advanced Drug Delivery Reviews, 64, 223-236. | |
| dc.relation.referencesen | 3. Seliktar, D. (2012). Designing cell-compatible hydrogels for biomedical applications. Science, 336 (6085), 1124–1128. | |
| dc.relation.referencesen | 4. Hamidi, M., Azadi, A., Rafiei, P. (2008). Hydrogel nanoparticles in drug delivery. Advanced Drug Delivery Reviews, 60, 1638-1649. | |
| dc.relation.referencesen | 5. Vasilev, A. E., Krasnyuk, I. I., Ravikumar, S. (2001). Transdermalnyie terapevticheskie sistemyi dostavki lekarstvennyih veschestv. Himikofarmatsevticheskiy zhurnal, 35(11), 29-42. | |
| dc.relation.referencesen | 6. Samchenko, Yu. M., Pasmurtseva, N. A., Ulberg Z. R. (2007). Diffuziya lekarstvennyih preparatov iz gidrogelevyih nanoreaktorov. Dopovidi NAN Ukrayini, 6, 143-148. | |
| dc.relation.referencesen | 7. Sekine, Y.,Moritani, Y., Fukazawa, T. I., Sasaki, Y., Akiyoshi, K. (2012). A hybrid hydrogel biomaterial by nanogel engineering: bottom-up design with nanogel and liposome building blocks to develop a multidrug delivery system. Advanced healthcare materials, 1(6), 722-728. | |
| dc.relation.referencesen | 8. Wen Zhao, Jin Xing, Cong Yang, Liu Yuying, Fu Jun. (2013). Degradable natural polymer hydrogels for articular cartilage tissue engineering. Journal of Chemical Technology & Biotechnology, 88(3), 327-339. | |
| dc.relation.referencesen | 9. Naahidi, S., Jafari, M., Logan, M., Wang, Y., Yuan, Y., Bae, H.,. Dixon, B, Chen, P. (2017). Biocompatibility of hydrogel-based scaffolds for tissue engineering applications. Biotechnology Advances, 35(5), 530-544. | |
| dc.relation.referencesen | 10. J. Tavakoli, Y. Tang Honey. (2017). PVA hybrid wound dressings with controlled release of antibiotics: Structural, physico-mechanical and in vitro biomedical studies. Materials Science and Engineering, 77, 318–325. | |
| dc.relation.referencesen | 11. J. Ramshaw, J. Werkmeister, V. Glatteur. (1995). Collagen based biomaterials. Biotechnol. Rev.,13, 336-382. | |
| dc.relation.referencesen | 12. Amir K. Miri, Hossein Goodarzi, Berivan Cecen, Shabir Hassan, Yu Shrike Zhang. (2018). Permeability mapping of gelatin methacryloyl hydrogels. Acta Biomaterialia,77, 38-47. | |
| dc.relation.referencesen | 13. Nosova, N. G., Samarik, V. Ya., Varvarenko, S. M., Ferens, M. V., Voronovska, A. V., Nagornyak, M. I., Homyak, S. V., Nadashkevich, Z. Ya., Voronov, S. A. (2016). Polyacrylamide porous hydrogels – preparation and properties Voprosyi himii i himicheskoy tehnologii, 5-6, 78-86. | |
| dc.relation.referencesen | 14. Lavrova, I.S. (1983). Praktikum po kolloidnoy himii. Moscow., Vyisshaya shkola. | |
| dc.relation.referencesen | 15. Samchenko, Yu. M., Pasmurtseva, N. A., Ulberg, Z. R. (2010). Primenenie uf-spektroskopii dlya izucheniya diffuzii lekarstvennyih soedineniy iz gidrogeley meditsinskogo. Jurnal hromatografichnogo tovaristva,10(1), 4-24. | |
| dc.citation.issue | 2 | |
| dc.citation.spage | 154 | |
| dc.citation.epage | 158 | |
| dc.coverage.placename | Lviv | |
| dc.coverage.placename | Lviv | |
| Appears in Collections: | Chemistry, Technology and Application of Substances. – 2019. – Vol. 2, No. 2
|
