| DC Field | Value | Language |
|---|
| dc.contributor.author | Kola, Anand Kishore | |
| dc.contributor.author | Mekala, Mallaiah | |
| dc.contributor.author | Goli, Venkat Reddy | |
| dc.date.accessioned | 2019-06-21T07:57:53Z | - |
| dc.date.available | 2019-06-21T07:57:53Z | - |
| dc.date.created | 2018-01-20 | |
| dc.date.issued | 2018-01-20 | |
| dc.identifier.citation | Kola A. K. Optimization studies on biosynthesis of citric acid by one-factor-at-a-time / Anand Kishore Kola, Mallaiah Mekala, Venkat Reddy Goli // Chemistry & Chemical Technology. — Lviv : Lviv Politechnic Publishing House, 2018. — Vol 12. — No 4. — P. 511–518. | |
| dc.identifier.uri | https://ena.lpnu.ua/handle/ntb/45198 | - |
| dc.description.abstract | Проведено оцінювання чинників процесу біо-
синтезу лимонної кислоти, та проаналізовано їх вплив на резуль-
тат процесу. Встановлено, що такі чинники, як початкова
концентрація сахарози, концентрація метанолу, концентрація
інокуляту, рН вихідного середовища, вірогідність спору,
швидкість обертання мішалки, період інкубації, температура
бродіння, розмір частинок, швидкість потоку кисню та
вологість мають значний вплив на процес. З використанням
експериментального дизайну Плакетта-Бурмана з одинадцяти
чинників визначено ті, які мають найбільший вплив на процес:
початкова концентрація сахарози, рН вихідного середовища,
швидкість обертання мішалки, інкубаційний період,
температура бродіння та витрата кисню. За допомогою
монотетичного аналізу експериментально підтверджений та
критично оцінений вплив чинників на вихід лимонної кислоти. | |
| dc.description.abstract | 1In the presented study, the significant operating
variables regarding biosynthesis of citric acid process
were assessed and their effects on the process yield were
analysed. These variables, namely, initial sucrose
concentration, methanol concentration, inoculum density,
initial medium pH, spore age, stirrer speed, incubation
period, fermentation temperature, particle size distribution,
oxygen flow rate, and moisture content have significant
influence on bioprocess of citric acid production.
Plackett-Burman approach was used to determine the
most significant variables, which predominantly influence
the citric acid production process. Out of the eleven
variables, initial sucrose concentration, initial medium pH,
stirrer speed, incubation period, fermentation temperature,
and oxygen flow rate were found to be significant. The
effect of the significant variables on the yield of citric acid
has been validated experimentally by one-factor-at-a-time
empirical optimization technique. The optimum
conditions have been determined. The effect of each
variable on the yield of citric acid was analysed critically. | |
| dc.format.extent | 511-518 | |
| dc.language.iso | en | |
| dc.publisher | Lviv Politechnic Publishing House | |
| dc.relation.ispartof | Chemistry & Chemical Technology, 4 (12), 2018 | |
| dc.relation.uri | https://doi.org/10.1016/j.jfoodeng.2004.10.006 | |
| dc.relation.uri | https://doi.org/10.1016/j.jbiotec.2004.01.007 | |
| dc.relation.uri | https://doi.org/10.1016/S1567-1356(02)00188-5 | |
| dc.relation.uri | https://doi.org/10.1007/BF00454376 | |
| dc.relation.uri | https://doi.org/10.1007/BF00255358 | |
| dc.relation.uri | https://doi.org/10.1016/S0141-0229(97)00041-0 | |
| dc.relation.uri | https://doi.org/10.1016/B978-0-444-63662-1.00025-7 | |
| dc.relation.uri | https://doi.org/10.1016/j.lwt.2012.05.016 | |
| dc.relation.uri | https://doi.org/10.1016/j.biombioe.2013.02.034 | |
| dc.relation.uri | https://doi.org/10.1016/j.lwt.2004.04.014 | |
| dc.relation.uri | https://doi.org/10.1016/j.sjbs.2012.01.004 | |
| dc.relation.uri | https://doi.org/10.1002/(SICI)1097-0290(19990705)64:1<92::AIDBIT10>3.0.CO;2-8 | |
| dc.relation.uri | https://doi.org/10.1002/bit.1175 | |
| dc.relation.uri | https://doi.org/10.1021/bp000167w | |
| dc.relation.uri | https://doi.org/10.2225/vol9-issue4-fulltext-7 | |
| dc.relation.uri | https://doi.org/10.1093/biomet/33.4.305 | |
| dc.relation.uri | https://doi.org/10.3168/jds.S0022-0302(58)91152-4 | |
| dc.relation.uri | https://doi.org/10.1021/ac60147a030 | |
| dc.relation.uri | https://doi.org/10.1042/bst0181020 | |
| dc.relation.uri | https://doi.org/10.1007/PL00009115 | |
| dc.relation.uri | https://doi.org/10.1016/0141-0229(86)90008-6 | |
| dc.relation.uri | https://doi.org/10.1007/s002530051651 | |
| dc.subject | лимонна кислота | |
| dc.subject | сахароза | |
| dc.subject | період інкубації | |
| dc.subject | ферментація | |
| dc.subject | оптимізація | |
| dc.subject | монотетичний аналіз | |
| dc.subject | citric acid | |
| dc.subject | sucrose | |
| dc.subject | incubation time | |
| dc.subject | fermentation | |
| dc.subject | optimization | |
| dc.subject | one-factor-at-a-time method | |
| dc.title | Optimization studies on biosynthesis of citric acid by one-factor-at-a-time | |
| dc.title.alternative | Оптимізація біосинтезу лимонної кислоти за допомогою монотетичного аналізу чинників | |
| dc.type | Article | |
| dc.rights.holder | © Національний університет „Львівська політехніка“, 2018 | |
| dc.rights.holder | ©Kola A., Mekala M., Goli V., 2018 | |
| dc.contributor.affiliation | National Institute of Technology, India | |
| dc.contributor.affiliation | BV Raju Institute of Technology, India | |
| dc.format.pages | 8 | |
| dc.identifier.citationen | Kola A. K. Optimization studies on biosynthesis of citric acid by one-factor-at-a-time / Anand Kishore Kola, Mallaiah Mekala, Venkat Reddy Goli // Chemistry & Chemical Technology. — Lviv : Lviv Politechnic Publishing House, 2018. — Vol 12. — No 4. — P. 511–518. | |
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| dc.relation.referencesen | [2] Kursat O., Gokhan D., Ahmet Y., J. Food Eng., 2005, 70, 518.https://doi.org/10.1016/j.jfoodeng.2004.10.006 | |
| dc.relation.referencesen | [3] Crolla A., Kennedy K., J. Biotechnol., 2004, 110, 73.https://doi.org/10.1016/j.jbiotec.2004.01.007 | |
| dc.relation.referencesen | [4] Kamzolova S, Shishkanova N., Murgunov I., Finoginova T.:FEMS Yeast Res., 2003, 3, 217. https://doi.org/10.1016/S1567-1356(02)00188-5 | |
| dc.relation.referencesen | [5] HossainM., Brooks J., Maddox I., Appl. Microbiol. Biotechnol.,1984, 19, 393. https://doi.org/10.1007/BF00454376 | |
| dc.relation.referencesen | [6] Xu D., Madrid C., Rohr M., Kubicek C., Appl. Microb. Biotechnol., 1989, 30, 553. https://doi.org/10.1007/BF00255358 | |
| dc.relation.referencesen | [7] Roukas T., Kotzekidou P., EnzymeMicrob. Technol., 1997, 21,273. https://doi.org/10.1016/S0141-0229(97)00041-0 | |
| dc.relation.referencesen | [8] Vandenberghe L., Rodrigues C., de Carvalho J. et al., Production and Application of Citric Acid [in:] Current Developments in Biotechnology and Bioengineering: Production, Isolation and Purification of Industrial Products. Elsevier 2016, 557-575. https://doi.org/10.1016/B978-0-444-63662-1.00025-7 | |
| dc.relation.referencesen | [9] Angumeenal A., Venkappayya D., LWT – Food Sci Technol.2013, 50, 367. https://doi.org/10.1016/j.lwt.2012.05.016 | |
| dc.relation.referencesen | [10] Betiku E., Adesina O., Biomass Bioenerg., 2013, 55, 350.https://doi.org/10.1016/j.biombioe.2013.02.034 | |
| dc.relation.referencesen | [11] Angumeenal AR, Venkappayya D. LWT Food Sci. Technol.2005, 38, 89. https://doi.org/10.1016/j.lwt.2004.04.014 | |
| dc.relation.referencesen | [12]Mostafa Y., Alamri S., Saudi J. Biol. Sci., 2012, 19, 241. https://doi.org/10.1016/j.sjbs.2012.01.004 | |
| dc.relation.referencesen | [13] Ooijkaas L., Wilkinson E., Tramper J., Buitelaar R., Biotechnol. Bioeng., 1999, 64, 92.https://doi.org/10.1002/(SICI)1097-0290(19990705)64:1<92::AIDBIT10>3.0.CO;2-8 | |
| dc.relation.referencesen | [14]Wen Z., Chen F., Biotechnol. Bioeng., 2001, 75, 159.https://doi.org/10.1002/bit.1175 | |
| dc.relation.referencesen | [15] Li C., Bai J., Li W., Cai Z., Ouyang F. Biotechnol. Prog., 2001,17, 366. https://doi.org/10.1021/bp000167w | |
| dc.relation.referencesen | [16] Duta F., de Franca F., Lopez L.-M: Electron. J. Biotechnol.,2006, 9, 391. https://doi.org/10.2225/vol9-issue4-fulltext-7 | |
| dc.relation.referencesen | [17] Plackett R., Burman J., Biometrika, 1946, 33, 305.https://doi.org/10.1093/biomet/33.4.305 | |
| dc.relation.referencesen | [18]Montgomery D., Design and Analysis of Experiments, 6th edn. John Wiley & Sons 2005, Ch. 11. | |
| dc.relation.referencesen | [19]Marrier J., Boulet M., J. Dairy Sci., 1958, 41, 1683.https://doi.org/10.3168/jds.S0022-0302(58)91152-4 | |
| dc.relation.referencesen | [20]Miller G., Anal. Chem., 1959, 31, 426.https://doi.org/10.1021/ac60147a030 | |
| dc.relation.referencesen | [21]MatteyM., Allan A., Biochem. Soc. Trans., 1990, 18, 1020.https://doi.org/10.1042/bst0181020 | |
| dc.relation.referencesen | [22] Pazouki M., Felse P., Sinha J., Panda T., Bioproc. Eng., 2000,22, 353. https://doi.org/10.1007/PL00009115 | |
| dc.relation.referencesen | [23] Pessoa D., Diasde C., Angela C., Revista deMicrobiologia,1982, 13, 225. | |
| dc.relation.referencesen | [24] Shadafza D., Ogawa T., Fazeli A., Hakko Kogaku Zasshi,1976, 54, 65. | |
| dc.relation.referencesen | [25] DawsonM., Maddox I., Brooks J., Enzym. Microb. Technol.,1986, 9, 37. https://doi.org/10.1016/0141-0229(86)90008-6 | |
| dc.relation.referencesen | [26] Sanjay K., Sharma P., J. Microb., 1994, 23, 211. | |
| dc.relation.referencesen | [27] Arzumanov T., Shishkanova N., Finogenova T., Appl. Microbiol. Biotechnol., 2000, 53, 525.https://doi.org/10.1007/s002530051651 | |
| dc.citation.journalTitle | Chemistry & Chemical Technology | |
| dc.citation.volume | 12 | |
| dc.citation.issue | 4 | |
| dc.citation.spage | 511 | |
| dc.citation.epage | 518 | |
| dc.coverage.placename | Lviv | |
| Appears in Collections: | Chemistry & Chemical Technology. – 2018. – Vol. 12, No. 4
|
