The study of the kinetic and thermodynamic of the blood serum properties free- radical oxidation lipids applying the method of chemiluminescence

Abstract

We investigated the physical parameters of chemical reactions which take place in blood serum (BS) at the chemiluminescence (CL) accompanying the process of peroxide oxidization of lipids. The emission intensity, wavelength, lifetime and energy of activation of the CL BS are sensitive to the pathologies. Under investigation CL spectrum it was found essential distinctions in the luminescence intensity in the presence of pathological processes such as tuberculosis and cancer. It was established that the ketonic compounds luminescence. Using a Stern-Volmer the lifetime of excited states equation was found. The data obtained suggest that ketones are in triplet states make the main contribution into CL BS.. An empirical Arrhenius equation for FRO was offered. Dependences of total chemilum inescence on the temperature were estimated. The energy of activation was determined differences of pathological processes were found. It is shown that this parameters change under the condition of pathological processes such as tuberculosis and cancer.