https://oldena.lpnu.ua/handle/ntb/40532| Title: | Anthraquinonylhydrazones of α-active ketones and β-carbonyl-containing compunds: synthesis and antioxidant activity |
| Authors: | Kopak, Nazar Stasevych, Maryna Zvarych, Viktor Deniz, Nahide Gulsah Sayil, Cigdem Ozyurek, Mustafa Guclu, Kubilya Vovk, Mykhailo Novikov, Volodymyr |
| Affiliation: | Lviv Polytechnic National University Istanbul University, TURKEY, Istanbul Division of Analytical Chemistry, TURKEY, Istanbul Department of Mechanisms of Organic Reactions, UKRAINE, Kyiv |
| Bibliographic description (Ukraine): | Anthraquinonylhydrazones of α-active ketones and β-carbonyl-containing compunds: synthesis and antioxidant activity / Nazar Kopak, Maryna Stasevych, Viktor Zvarych, Nahide Gulsah Deniz, Cigdem Sayil, Mustafa Ozyurek, Kubilya Guclu, Mykhailo Vovk, Volodymyr Novikov // Litteris et Artibus : proceedings, 23–25 November, 2017. — Lviv : Lviv Polytechnic Publishing House, 2017. — P. 32–33. — (6th International academic conference «Chemistry & chemical technology 2017» (CCT-2017)). |
| Bibliographic description (International): | Anthraquinonylhydrazones of α-active ketones and β-carbonyl-containing compunds: synthesis and antioxidant activity / Nazar Kopak, Maryna Stasevych, Viktor Zvarych, Nahide Gulsah Deniz, Cigdem Sayil, Mustafa Ozyurek, Kubilya Guclu, Mykhailo Vovk, Volodymyr Novikov // Litteris et Artibus : proceedings, 23–25 November, 2017. — Lviv : Lviv Polytechnic Publishing House, 2017. — P. 32–33. — (6th International academic conference «Chemistry & chemical technology 2017» (CCT-2017)). |
| Is part of: | Litteris et Artibus : матеріали, 2017 Litteris et Artibus : proceedings, 2017 |
| Conference/Event: | 7th International youth science forum «Litteris et Artibus» |
| Journal/Collection: | Litteris et Artibus : матеріали |
| Issue Date: | 23-Dec-2017 |
| Publisher: | Видавництво Львівської політехніки Lviv Polytechnic Publishing House |
| Place of the edition/event: | Львів Lviv |
| Temporal Coverage: | 23–25 листопада 2017 року 23–25 November, 2017 |
| Keywords: | 9 10-anthraquinone diazonium salt hydrazone α-active ketones β-carbonylcontaining compunds antioxidant activity |
| Number of pages: | 2 |
| Page range: | 32-33 |
| Start page: | 32 |
| End page: | 33 |
| Abstract: | An effective method for the synthesis of 1-anthraquinonyl hydrazones containing the acyl- and/or ethoxycarbonyl, carbo- and heterocyclic fragments in the ylidene moiety has been shown, which are convenient reagents for further chemical transformations. Investigation of the antioxidant activity of hydrazones has allowed to identify promising compounds that can be suggested for further research as antioxidant substances. |
| URI: | https://ena.lpnu.ua/handle/ntb/40532 |
| ISBN: | 978-966-941-108-2 |
| Copyright owner: | © Національний університет “Львівська політехніка”, 2017 |
| References (Ukraine): | [1] N. Belskaya, W. Dehaen, V. Bakulev, “Synthesis and properties of hydrazones bearing amide, thioamide and amidine functions,” Arkivoc, vol. I, pp. 275-332, 2010. [2] R. Ali, A. Marella, T. Alam, R. Naz, M. Akhter, Md. Shaquiquzzaman, R. Saha, O. Tanwar, M. Alam, J. Hooda, “Review of biological activities of hydrazones,” Indones. J. Pharm., vol. 23, pp. 193-202, 2012. [3] Q.A. Acton, Ed., Anthraquinones. Advances in Research and Application. Atlanta : Scholarly Editions,2013. [4] S. Arai, S. Kato, M.B. Hida, “Anthraquinone pharmaceutical compounds and uses therefor,” J. Chem. Soc. Jpn., vol. 58, p. 1458, 1985. [5] I. Antonini, P. Polucci, D. Cola, G. Palmieri, S. Martelli, M. Bon-temps-Gracz, “Synthesis of 9,10-anthraquinone monoalkylaminoalkylhydrazones as potential antitumor drugs,” Farmaco, vol. 48, pp. 1641-1648, 1993. [6] V.A. Loskutov, “Reaction of anthrone and its 1-and 4- substituted derivatives with sulfur in the presence of nucleophiles,” Russ. J. Org. Chem., vol. 36, pp. 1478-1481, 2000. [7] M. Regitz, “Reaktionen aktiver Methylen-verbindungen mit Aziden, III. Über die Diazo-, Azino- und Triphenylphosphazino-Derivate des Anthrons und Thioxanthen-S-dioxids,” Chem. Ber., vol. 97, pp. 2742-2754, 1964. [8] S.L. Vorob’eva, V.N. Buyanov, I.I. Levina, N.N. Suvorov, “Naphthindoles. 2. Naphtho[2,3-e]indole-4,9- diones and naphtho[2,3-f]indole-5,10-diones,” Chem. Heterocycl. Compd., vol. 25, pp. 646–649, 1989. [9] K. MeeKyoung, D.F. Wiemer, “EDC-mediated condensations of 1-chloro-5-hydrazino-9, 10-anthracenedione,1-hydrazino-9,10-anthracenedione, and the corresponding anthrapyrazoles,” Tetrahedron Lett., vol. 45,pp. 4977- 4980, 2004. [10]V. Zvarych, M. Stasevych, V. Lunin, N.G. Deniz, C. Sayil, M. Ozyurek, K. Guclu, M. Vovk, V. Novikov, “Synthesis and investigation of antioxidant activity of the dithiocarbamate derivatives of 9,10-anthracenedione”, Monatsh. Chem., vol. 147, pp. 2093-2101,2016. [11]R. Apak, K. Güçlü, M. Özyürek, S.E. Karademir, “Novel total antioxidant capacity index for dietary polyphenols and vitamins C and E, using their cupric ion reducing capability in the presence of neocuproine: CUPRAC method,” J. Agric. Food Chem., vol.52,pp.7970-7981, 2004. [12]B. Bekdeşer, M. Özyürek, K. Güçlü, F. Üstün Alkan, R. Apak,“Development of a new catalase activity assay for biological samples using optical CUPRAC sensor,” Spectrochim. Acta Part A, vol. 132, pp. 485-490, 2014. |
| References (International): | [1] N. Belskaya, W. Dehaen, V. Bakulev, "Synthesis and properties of hydrazones bearing amide, thioamide and amidine functions," Arkivoc, vol. I, pp. 275-332, 2010. [2] R. Ali, A. Marella, T. Alam, R. Naz, M. Akhter, Md. Shaquiquzzaman, R. Saha, O. Tanwar, M. Alam, J. Hooda, "Review of biological activities of hydrazones," Indones. J. Pharm., vol. 23, pp. 193-202, 2012. [3] Q.A. Acton, Ed., Anthraquinones. Advances in Research and Application. Atlanta : Scholarly Editions,2013. [4] S. Arai, S. Kato, M.B. Hida, "Anthraquinone pharmaceutical compounds and uses therefor," J. Chem. Soc. Jpn., vol. 58, p. 1458, 1985. [5] I. Antonini, P. Polucci, D. Cola, G. Palmieri, S. Martelli, M. Bon-temps-Gracz, "Synthesis of 9,10-anthraquinone monoalkylaminoalkylhydrazones as potential antitumor drugs," Farmaco, vol. 48, pp. 1641-1648, 1993. [6] V.A. Loskutov, "Reaction of anthrone and its 1-and 4- substituted derivatives with sulfur in the presence of nucleophiles," Russ. J. Org. Chem., vol. 36, pp. 1478-1481, 2000. [7] M. Regitz, "Reaktionen aktiver Methylen-verbindungen mit Aziden, III. Über die Diazo-, Azino- und Triphenylphosphazino-Derivate des Anthrons und Thioxanthen-S-dioxids," Chem. Ber., vol. 97, pp. 2742-2754, 1964. [8] S.L. Vorob’eva, V.N. Buyanov, I.I. Levina, N.N. Suvorov, "Naphthindoles. 2. Naphtho[2,3-e]indole-4,9- diones and naphtho[2,3-f]indole-5,10-diones," Chem. Heterocycl. Compd., vol. 25, pp. 646–649, 1989. [9] K. MeeKyoung, D.F. Wiemer, "EDC-mediated condensations of 1-chloro-5-hydrazino-9, 10-anthracenedione,1-hydrazino-9,10-anthracenedione, and the corresponding anthrapyrazoles," Tetrahedron Lett., vol. 45,pp. 4977- 4980, 2004. [10]V. Zvarych, M. Stasevych, V. Lunin, N.G. Deniz, C. Sayil, M. Ozyurek, K. Guclu, M. Vovk, V. Novikov, "Synthesis and investigation of antioxidant activity of the dithiocarbamate derivatives of 9,10-anthracenedione", Monatsh. Chem., vol. 147, pp. 2093-2101,2016. [11]R. Apak, K. Güçlü, M. Özyürek, S.E. Karademir, "Novel total antioxidant capacity index for dietary polyphenols and vitamins C and E, using their cupric ion reducing capability in the presence of neocuproine: CUPRAC method," J. Agric. Food Chem., vol.52,pp.7970-7981, 2004. [12]B. Bekdeşer, M. Özyürek, K. Güçlü, F. Üstün Alkan, R. Apak,"Development of a new catalase activity assay for biological samples using optical CUPRAC sensor," Spectrochim. Acta Part A, vol. 132, pp. 485-490, 2014. |
| Content type: | Conference Abstract |
| Appears in Collections: | Litteris et Artibus. – 2017 р. |
| File | Description | Size | Format | |
|---|---|---|---|---|
| 2017_Kopak_N-Anthraquinonylhydrazones_of_32-33.pdf | 238.45 kB | Adobe PDF | View/Open | |
| 2017_Kopak_N-Anthraquinonylhydrazones_of_32-33__COVER.png | 1.51 MB | image/png | View/Open |
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