https://oldena.lpnu.ua/handle/ntb/26998| Title: | Synthesis of new heterocyclic compounds based on 1,4-naphthoquinones and azomethines of α-amino acids |
| Authors: | Kudrinetska, Anastasiia Shakh, Yurii Bolibrukh, Khrystyna Karkhut, Andrii Lytvyn, Bohdan Polovkovych, Sviatoslav |
| Bibliographic description (Ukraine): | Synthesis of new heterocyclic compounds based on 1,4-naphthoquinones and azomethines of α-amino acids / Anastasiia Kudrinetska, Yurii Shakh, Khrystyna Bolibrukh, Andrii Karkhut, Bohdan Lytvyn, Sviatoslav Polovkovych // Хімія та хімічні технології : матеріали IІI Міжнародної конференції молодих вчених CCT-2013, 21–23 листопада 2013 року, Україна, Львів / Національний університет "Львівська політехніка". – Львів : Видавництво Львівської політехніки, 2013. – С. 106–107. – (4-й Міжнародний молодіжний фестиваль науки "Litteris et Artibus"). – Bibliography: 16 titles. |
| Issue Date: | 2013 |
| Publisher: | Видавництво Львівської політехніки |
| Keywords: | heterocyclic compounds 1,4-naphthoquinones azomethines of α-amino acids anticancer agents "drug-like" compounds 1,3-dypolar cycloaddition reaction |
| Abstract: | Analysed the literature sources to establish the basic ˝skafolds ˝, necessary for the design of "drugs-like molecules." Created the combinatorial library of new heterocyclic derivatives of 1,4-naphthoquinone. A docking study for determining structure leaders was conducted, ways of optimization the chemical structures to enhance the biological activity were determined. Designed by methods of obtaining a new heterocyclic derivatives based on 1,4-naphthoquinone and conducted search including effective anti-cancer agents. |
| URI: | https://ena.lpnu.ua/handle/ntb/26998 |
| Content type: | Article |
| Appears in Collections: | Хімія та хімічні технології (CCT-2013). – 2013 р. |
| File | Description | Size | Format | |
|---|---|---|---|---|
| 039-106-107.pdf | 267.29 kB | Adobe PDF | View/Open |
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